A Graph-to-Image Representation Framework for Modeling Splice-Site Responses in SMN2 Exon 7 Variants

Submitted SVGI conference paper integrating ΔPSI, replicate-normalized responsiveness, weighted co-splicing structure, GAT-derived geometry, Gromov–Wasserstein graph-to-grid mapping, and an AlexNet-style CNN to model risdiplam and branaplam responses across 285 SMN2 exon 7 splice-site variants.